本片根据纽约市的英籍神经医师奥利佛·萨克斯(Oliver Sacks)的同名回忆录改编。1969年,羞怯内向但对实验充满热忱的脑科医生马尔科姆·塞尔(罗宾·威廉姆斯 Robin Williams 饰)来到纽约市布朗克斯区一家医院,对院内的强直性昏厥证患者进行治疗。在护士埃莉诺(朱莉·卡夫娜 Julie Kavner 饰)的帮助和鼓励下,塞尔医生对病人大胆用药,使一群昏厥几十年的患者重获新生,尤其对患者伦纳德·洛(罗伯特·德尼罗 Robert De Niro)效果尤为明显。但令人意外的是,患者们在苏醒后不久,又纷纷出现了病情恶化的趋势……
本片获奥斯卡最佳影片、最佳男主角(罗伯特·德尼罗)和最佳改编剧本奖提名,并获金球奖剧情类影片最佳男主角提名(罗宾·威廉姆斯)
Harry Moseby (Gene Hackman), a worn-out private detective, is hired to look for a 16-year-old girl who has run away from the luxury home of her mother, formerly a small-time actress in Los Angeles. The more the weary cynic tries to get under the surface of the seemingly simple case, the harder it is for him to find his bearings among the lies and deceptions that surround him. Eight years after the key New Hollywood film Bonnie and Clyde, Arthur Penn and Gene Hackman reunited to collaborate on what was to become one of the most undervalued films of the decade. Like Polanski in Chinatown or Altman in The Long Goodbye, in his revisionist film noir, Penn also allows the 1940s classic genre to pervade the complex reality of the 1970s. The feelings of bitterness and emptiness in the modern Chandleresque protagonist originate not only in the “public” sphere of the strange, increasingly convoluted case, but in his private life as well (boyhood trauma, a broken marriage). As Moseby remarks of a sporting event, “nobody’s winning … one side is just losing slower than the other.”